Melatonin doesn't just improve sleep, but has a lot of neuroprotective effects. They say it may be that P does not reduce ability to produce melatonin, but PD decreases the number of melatonin receptors.
https://www.chronobiology.com/parkinsons-disease-and-sleep-disorders-can-melatonin-help/
Melatonin helps mitochondria complex 1
Here's another article on melatonin, but also has a list of chemicals that work in animal models of PD. This list aimed at better mitochondrial function, but also most of them have other effects like iron-chelating, antioxidant, and preventing protein misfolding.
http://www.intechopen.com/books/a-synopsis-of-parkinson-s-disease/melatonin-in-parkinson-s-disease
Acetyl-L-carnitine
Aspirin
(acetylsalicylic acid)
creatine
Caffeine
Creatine
Curcumin
(–)-Epigallocatechin gallate
(EGCG)
(R)-Lipoic acid
Melatonin
MLT)
(–)-Nicotine
Nicotinamide
Resveratrol
Riluzole
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